منابع مشابه
Caveolin-1 in sarcomas: friend or foe?
Sarcomas represent a heterogeneous group of tumors with a complex and difficult reproducible classification. Their pathogenesis is poorly understood and there are few effective treatment options for advanced disease. Caveolin-1 is a multifunctional scaffolding protein with multiple binding partners that regulates multiple cancer-associated processes including cellular transformation, tumor grow...
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Particularly in the field of advertising and in popular scientific journals, antioxidants such as β-carotene (from carrots) or lycopenes (from tomatoes) and the vitamins C and E are one-sidedly portrayed as substances capable of offering protection against cancer or ageing because they diminish or prevent the effects of free radicals. However, free radicals should by nomeans be considered as be...
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متن کاملNanofibers: Friend or Foe?
Alke Petri-Fink 1, Barbara Rothen-Rutishauser 1 and Martin J. D. Clift 1,2,* 1 BioNanomaterials, Adolphe Merkle Institute, University of Fribourg, Rte de l’Ancienne Papeterie, Marly 1, 1723 Fribourg, Switzerland; [email protected] (A.P.-F.); [email protected] (B.R.-R.) 2 Swansea University Medical School, Singleton Park Campus, Swansea University, Swansea, Wales SA2 8PP, UK * Corresponde...
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In this issue of Blood, Xu and colleagues provide evidence that suggests PAI-1 is cardioprotective as demonstrated by the observation that spontaneous cardiac fibrosis occurs in aging PAI-1– deficient (PAI-1 / ) mice, preceded by early changes in cardiac vascular barrier integrity, enhanced inflammation, dysregulated extracellular matrix remodeling, and, eventually, pervasive fibrosis and compr...
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ژورنال
عنوان ژورنال: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
سال: 2014
ISSN: 0896-8608,1718-4304
DOI: 10.3747/pdi.2014.00013